The White House said the activities were similar to those made before a suspected chemical attack in April.
The US statement warned President Bashar al-Assad of "a heavy price" if another strike occurred.
It said "another chemical weapons attack by the Assad regime" was likely to result "in the mass murder of civilians".
The statement added: "As we have previously stated, the United States is in Syria to eliminate the Islamic State of Iraq and Syria. If, however, Mr Assad conducts another mass murder attack using chemical weapons, he and his military will pay a heavy price."