Tailor-Made Cancer 'Vaccine' Proves Safe: Trial Results
Two experimental treatments for skin cancer, tailor-made to target a particular patient's tumours, proved safe in small-scale trials, their developers reported Wednesday, AFP reports.
The vaccines also triggered an immune response to tumour cells, they said, although this does not necessarily equate to a cure.
These are the first drug trials in humans with personalised vaccines directed at neoantigens -- molecules, caused by DNA mutations, found in cancer cells. The results of both were published in the journal Nature.
Unlike a traditional vaccine that prevents disease, the aim of NeoVax is to prevent cancer from recurring in melanoma skin cancer patients after their tumours have been surgically removed.
For the time being, the team cannot conclude that their vaccine has this effect.
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